Neural Computing and Applications - This research article corroborates the working of a model reference adaptive model (MRAS) with fractional-order proportional-integral (FOPI $$^\lambda $$ )-based... 相似文献
This study was to separate and purify antidiabetic and angiotensin-converting enzyme (ACE) inhibitory peptides from Lactiplantibacillus plantarum KGL3A fermented camel milk. After 48 h of fermentation at 37°C, ɑ-amylase inhibition, ɑ-glucosidase inhibition, lipase inhibition and ACE inhibitory activities were 80.94%, 64.45%, 63.93%, and 77.53%, respectively in fermented camel milk. Optimisation of growth condition for the evaluation of maximum peptide production was evaluated by measuring proteolytic activity (O-phthalaldehyde, OPA method) with different inoculation rates and incubation times and highest proteolytic activity (9.21 mg/mL) was observed after 48 h of fermentation at 2.5% rate of inoculation. The antidiabetic and ACE inhibitory activity of 3 kDa permeate fraction were higher as compared with other fractions. Purification of antidiabetic and ACE inhibitory peptides from fermented camel milks was performed through sodium dodecyl-sulphate polyacrylamide gel electrophoresis, and 2-dimensional polyacrylamide gel electrophoresis and maximum number of protein bands were present in between 25 and 10 kDa. The generated peptide sequences were matched with antihypertensive peptide database (AHTPDB) and BIOPEP databases for confirming the antidiabetic and ACE inhibitory activity. Peptides, that is. TDVMPQWW and MMSLVSLLLVGILFPTIQAK were having highest peptide ranker score among the all sequences. Furthermore, anti-inflammatory activity (TNF-α, IL-6 and IL-1β) of fermented camel milk was evaluated in macrophage cell line RAW 264.7 (Ralph and William's cell line). Furthermore, peptides were predicted to have improved binding affinity against Human Angiotensin converting enzyme (hACE) through molecular docking. 相似文献
In the present work, numerical simulation has been done to analyze transients in gas flow and pressure in a horizontal straight pipe. For a single gas pipeline, eight representative cases corresponding to different causes of transient behaviour are simulated to predict unsteady state flow and the evolution of pressure profiles. The numerical results show that depending upon the pipe dimensions and operating variables such as pressure and gas flow rate, transient effects in the pipeline may last for a long time and/or over significant length of pipe. The simulations predict an initial surge in gas flow rate greater than the final steady‐state value if the pressure drop across the pipe is increased. Similarly, initial flow rate may decrease below the final steady‐state value if the pressure drop is decreased. In case of complete closure of a valve, oscillations in both pressure and mass flow rate are observed, which gradually decay and the steady state conditions of no flow are ultimately achieved. The present results are compared with a published work from the literature. A reasonably good agreement is found between these two predictions. The present study is of practical significance in safe design and operation of a gas delivery system. 相似文献
The performance of microwave components is sensitive to vibrations to some extent. Aside from the resonator, microwave cables, and connectors, bandpass filters, mechanical phase shifters, and some nonlinear components are the most sensitive. The local oscillator is one of the prime performance-limiting components in microwave systems ranging from simple RF receivers to advanced radars. The increasing present and future demand for low acceleration sensitive oscillators, approaching 10?13/g, requires a reexamination of sensitivities of basic nonoscillatory building-block components under vibration. The purpose of this paper is to study the phase-modulation (PM) noise performance of an assortment of oscillatory and nonoscillatory microwave components under vibration at 10 GHz. We point out some challenges and provide suggestions for the accurate measurement of vibration sensitivity of these components. We also study the effect of vibration on the amplitude-modulation (AM) noise. 相似文献
The rapid growth of new technologies resulted in a new city model, known as the famous “Smart City”. The main aim in this paper is to create a paradigm for building an energy efficient smart city. Wireless local area network (WLAN) controller that will be used by the city will be constructed in such a manner that when there will be no request from any node to the access point (AP), the AP will be send from active mode to sleep mode. In Qualnet7.2, with the help of three types of energy model generic, mica z and mica motes the energy consumption in three modes transmit, receive and sleep mode is analysed, where it is seen that energy consumption in sleep mode is much less than in any other modes. In this paper, we propose an algorithm where it is shown that the energy consumption in sleep mode is less than in any other modes.